Update on Glutathione Therapy with Dr. Nayan Patel
Tue, Mar 14, 2023 4:51PM • 1:42:22
SUMMARY KEYWORDS
glutathione, patients, levels, product, day, trial, mycobacterium, hours, study, put, glutathione levels, cytokines, sprays, parkinson, questions, inflammatory markers, gluten, glue, measure, liposomal
SPEAKERS
Bill Clearfield
Bill Clearfield 00:16
Yesterday I just I just sent off your video to be posted just just a little while ago. I was away for a week and I kind of got a little behind things so
00:30
that’s that’s right.
00:33
We haven’t so
Bill Clearfield 00:40
I’m assuming it went well. Oh, yes. Excellent. Okay, you guys all survived without me for a week.
00:50
Yeah, we managed our team. Okay. Okay. Your team took care of the rest
Bill Clearfield 01:02
on the
01:05
every week for it since
Bill Clearfield 01:05
you since you did the thing with the prostate thing I’ve been putting, you know when there’s anybody respond to it at all. Do you ever get any? Any of the doctors?
01:14
Yes, I don’t think it was through you though. I’ve had a German physician through the grapevine connect with me and I’m just reviewing his labs right now. Actually, I have it up in front of me. sollen German, I understand German but you know, the basic conversational German, not the medical German, so I’m trying to decipher this stuff. But yeah, he’s in bad shape. It’s it sounds like he had cancer a couple of years ago. He was treated looked okay. Then he got the job and now he has metastasis to the bone. He’s on like five different narcotics for the pain. He’s in real bad shape.
Bill Clearfield 01:54
Sorry to hear that. Yeah. Doctor. Dr. Patel is with us now. Dr. Patel. Hi, how
01:59
are you? Setups I just lost him. earlier.
Bill Clearfield 02:05
Yeah. So thank you for joining for joining us again. And I hope all as well with you.
02:14
Yeah, it’s exciting time because I’m a clinical trials just got completed. And it’s, it’s, we’re in the writing phase right now. And so it’s not Alpha publication yet. But we are hoping that we should be done with the manuscript ready by end of April. Before and we already have the Journal of immunology already accepted our article to be reviewed so terrific. So it’s gonna be interesting.
Bill Clearfield 02:40
Okay. So, and are you getting a lot of prescriptions for in Clomiphene? Yes, we are. No, because the Clomiphene is nowhere to be found.
02:51
Yeah, so we have n clomifene. We have a limit of clomifene left but the prices go up to like almost eight bucks a tablet and used to be like a couple of bucks. Right? And so the
Bill Clearfield 03:02
used to be 60 cents.
03:04
Well, yeah, but recently in the last few years, it has been couple of bucks. But now that objective price to eight bucks a pill generic so it’s not there. There’s a construction happening right now. And so that’s what’s going that’s what’s driving the prices,
Bill Clearfield 03:22
which is the end how much is the end Coloma and Clomiphene
03:25
is not cheap either. But I believe that’s like, three bucks if I’m not wrong, so it’s much comparable in pricing.
Bill Clearfield 03:37
And that’s those differently, right?
03:41
Half the dose. So if you’re using 1225 milligrams of Clomid, the you can just go 12 and a half milligrams or give them a cyber 6.25 milligram and see how they behave, and then go up higher. But what I’m finding out is that when you do an Clomiphene or Clomid, or HCG, or whatever, it will raise your testosterone levels, no doubt about it. But the response is not there. Patients don’t feel good.
Bill Clearfield 04:08
Well, we’ve been using it for a long time and we use it in younger
04:11
guys. Yeah, that’s more mainly we use it for younger guys too. But they will raise the levels but they don’t feel the best. And that’s the that has been my clinical observation. I have nothing to backup in the sense that Hey, is it is it because there’s something else happening or not? Because it has risen testosterone levels? My theory is that raising testosterone level is not the answer all I think it’s what can we do to improve free bioavailable levels of testosterone there is.
Bill Clearfield 04:45
So, so we usually give them a little bit of boron that seems to help that lowers the binding globulins
04:52
but the boron is is it I don’t think the boron is illegal to be sold right or Buddha. Bar nickel, cobalt, Cobalt is a one. Sorry,
Bill Clearfield 05:01
I haven’t used cobalt.
05:03
Is great by the way. It’s really good product. But the problem is the Cobalt is really hard to get nutrition grade cobalt that can be used for patients. Let me see if I can share my slides and if that’s that’s possible,
Bill Clearfield 05:22
it was a really 15 years ago to the prosthetic companies with for hip replacements was putting cobalt in the hand and there was all sorts of problems with that. Ah
05:40
I’m trying to see if I can get some files already
Bill Clearfield 05:44
be there right down to the center of their share screen.
05:47
Yeah, but I have to clear my desktop first. Open the files. And then I can certainly so there you go. It’s there. Okay, perfect.
Bill Clearfield 06:03
So you have a few more minutes yet so. Okay,
06:07
so I’ll share with you you’re ready for it. Now Thanks for Thanks for having me over here. I know Jackie has been working with you to get Everything’s ready. And
Bill Clearfield 06:18
Jackie is an old friend. We’ve been through the wars together.
06:21
Oh, good. So upon Jackie’s recommendation, we are offering something good for the very first time to her audience. So we want to have a special price for them at the end just so that she hardware gets get some credit to it right all right. We’ll definitely do that for her but to do something
Bill Clearfield 06:41
for you Jackie. used to you know, come come as a as a rep and she bring her mother and you know, her mother would say you’re going to you’re going to use our stuff right?
06:58
Oh my gosh.
Bill Clearfield 07:01
I don’t mess around with mom.
07:04
Yeah, mom and the dogs came to everybody was that a two hour drive? I had to bring it to bring the fan down. Yeah.
07:18
I’ve made sure lighting is okay. I can see.
07:21
You’re good. All right. Perfect. Hey, Kent. Dr. Bill, how are you?
Bill Clearfield 07:28
I’m good. I got one of your one of your guys that you sent me. answered right away and we got him signed up.
07:35
Now Chris Miletus.
Bill Clearfield 07:37
I believe this I sent a message to you today that holds the yesterday and then the other guy I didn’t hear from
07:44
yet so remind me who it is. And I’ll follow up to Joe are li I don’t remember.
Bill Clearfield 07:53
I look it up during the thing and I’ll send you
07:57
that cool. Okay, thanks.
07:59
Hey, Kent. Hey. Aloha.
08:06
Is that Maria? Yes.
08:12
Fancy meet new year.
08:15
I’m always here.
Bill Clearfield 08:17
Only the best people show up with this
08:22
Dr. Maria, Maria is a good one.
Bill Clearfield 08:28
I think Maria has been on one with us before, hasn’t she? Yeah. Thanks. So
08:33
have you Maria.
08:36
Ah, you guys.
08:38
I don’t remember what I ate for dinner yesterday.
08:46
Pro Jones, that’s fine. You know, I
08:48
take pro drum I take glutathione I take everything that anybody has ever taught me about. But I think it’s just 1012 plates spinning in my head.
09:02
That could be let’s definitely put the tax on your on your short term memory. being super busy. Tonight, we
09:12
get the truth. Yay. Glutathione. Hey, I see we have shell Stein here. I keep trying to figure out who this guy is? Because he’s asking a bunch of important questions. So I hope somebody can give me a clue as to
09:32
what shells up to. Here you’re listening. Learning.
09:42
I want to learn more. So keeping.
09:47
Alright, I’ll get out of the way I know
09:50
you sound good. Dr. Andy.
09:53
Doing well doing well.
Bill Clearfield 09:56
You’re behaving yourself Andy.
09:59
Oh, man. If you only knew I think I have have a habit of not behaving myself. So we’ll see how far you guys want to get involved?
Bill Clearfield 10:15
Well, okay, it’s five o’clock. We’ll keep letting folks in as they show up. And so Dr. Nyah Patel is a pharmacist at Central drugs, correct? Yes, yes. And he’s got a an interest in glutathione. We’ve had some we’ve had some lectures from his group before. Dr. Yamani Yutani
10:47
you’re totally right. You’re totally
Bill Clearfield 10:49
right. Yeah, talk to the attorney. You know, he was at our conference last year. And he was well received, and I’m gonna let you just introduce yourself and mute everybody else mute themselves. And we’ll take it from there.
11:07
Absolutely. Thank you, Dr. clearfil. So I’m Dr. Nan Patel pharmacist for over 25 plus years. Compounding Pharmacist and in my research lab in my I look at my pharmacy as a research lab. And in the research lab, about 14 years ago, we discovered no way to deliver glutathione back then I had no idea what I had discovered. But, but my my pharmacist mind was there to make it a stable form of glutathione. Later on, I figured out how this glutathione was a not just a stable form, but what was a normal way to deliver interesting levels of glutathione immediately upon application through through skin and bypasses the gut and different ways to degrade the glue without so so we were able to do that part and as a clinical mind kick kicked in for the last 1214 years I all I’ve been doing is clinical outcomes. And now what we have is a novel way to deliver glutathione for the first time to improve intracellular levels. And so last few years I’ve been involved with a couple of institutions tried to figure out to do with the human trials we we had about a couple of years of snag in terms of getting through IRB for human trials, which we eventually got it last year. And so we just completed the first human trials. And what we are presenting today is the outcomes of the trial so that way, I think it will spark some interest at the same time. I think you will be amazed as I’m sure you’re already amazed about glutathione to begin with, but you might be probably be amazed to see how fast it is, is actually helping human bodies if it’s delivered in correct form. So without further ado, I want to start my presentation is this I will give you some ideas. If you have any questions while I’m presenting. Please either raise your hands or put in the chat box. And my goal is to answer as many questions as possible. So that way you when you leave today you I want to make sure that you have thoroughly informed about it. So let’s see if I can do those
13:44
all right. So
13:52
this research was done at Western University School of Medicine. It’s a deal program over there. Dr. Venkat Raman and his lab associates did this whole study. It was done over six months period of time for 30 patients. So we want to make sure that they get the proper credit for doing all the work. This slides were prepared by his team. And I’m just a narrative today but rest assured I’ve got the permission to use his slides completely. So whether it’s my name as a presenter, these The slides are prepared by Dr. Ivanka Trump and his assault lab associates completely. Okay, let’s see. No All right. So background we want to make sure that we go over what why do we do the study what what study objectives and the aim study design incorrectly? Criteria methods and protocols data collections results, acknowledgments and, and where do we go from here? So, Dr. Venkat Raman has been doing a lot of research when it comes to liposomal form of glue tired for at least I would say 15 years plus. And so he has done work with mycobacterium tuberculosis, HIV type two diabetes trials, both animal models, mostly animal models, and mostly in vitro. Studies. Only so has some done in vivo studies, because mostly all the studies that were done were in were in vitro, and of course lately, he’s been working with us on the topic of form of glutathione since it’s already commercially available so previous studies that he has published his probably published well over 15 studies, I believe, so if you just put PubMed his name, I think all his research is going to pop up when it comes to the glutathione. So his lab has been very active. In trying to understand glutathione and fortunately, unfortunately, other have you look at it, they’re working with liposomal technology, which which showed great promise. And with the new delivery system that we have. I think it’s going to accelerate the whole findings. So hopefully we are a little bit optimistic as to what this is going to hold in the future. But his work has been on mostly on the antibody probe activity. Has his work is has also included NAC as gluten precursor. Let me see. He’s worked with looking at all the markers to impact type two diabetes, also see if it has any activity on the T cells, helper cells for HIV populations, and so so and so forth, but keep in mind all these studies were done. It was in vitro studies. The latest publication what triggered this whole research was Dr. Ray Yutani, who has speak at this at this forum before on a podcast about AI and AI. He was there at your March last year convention in Las Vegas, I believe. So to present his findings on on on treatment for COVID 19. And one of the treatment current options where the limitations were the care graphs and how a novel alternative comparable agent like glutathione in the sacral testing complex can can be an adjunct product to the whole regimen. And so this is this is our this is currently been under a peer review process right now. And if anybody wants to be involved in the peer review process please kill send me your name. And I’ll I’ll forward it to the to the publishers that are looking for more reviewers of this article to see if it’s held holds any any validity to the to the statement that he’s trying to make. So So anyways, Goodwill is the name of the product. That’s that’s that’s the one who was used. It’s a combination of glutathione ascorbic acid cyclodextrins and some and some preservative agent, which is sorbets and ready should extract cyclodextrins that were used were combinations of GABA cyclodextrins and little bit of alpha beta. This is same cyclodextrin that Dr. Fauci used back in the late 80s, early 90s To really try to figure out how they can help with HIV patients. And of course, in vitro study shows that cyclodextrin has has tremendous effect as an antiviral properties. But in vivo studies failed miserably, all of them. And so, when, when we were doing all this work, we found out that the dextran molecules while he was stabilizing glutathione or glue that was also delivering cyclodextrin to the human body. And so that’s what the whole trigger by the COVID started for us. And so when Dr. italic did all the work at the University, he saw positive outcomes with that was using glutathione as a carrier mechanism to deliver cyclodextrin and in this case, we are using second dextran as a carrier to deliver glutathione so I believe the both work in symbiosis together to to achieve the outcomes for us and in this study, we also use a placebo solution, where the placebo was ascorbic acid and cyclodextrin. And, to our surprise, you’ll see the results of it that the small amount of ascorbic acid we had inside actually did not increase the gluten level significantly. So objective was just to basically look at absorption of blue dye because when we saw the results in the early on in 2020. We thought hey half How come this is working so fast? So our primary goal was looking at absorption glutathione through through us through your skin. an IRB basically wanted us to put in some immune responses because of growth and has shown some promise in improving immune modulators. So they asked us to do an in vitro study for mycobacterium Avium. I believe mycobacterium tuberculosis was not available at the time and so they they were asked, So we asked them to use mycobacterium Avium and this was upon request from the from the IRB board. So our aim was to determine how topical application glitter increases glutathione levels of literal increasing glutathione levels in the plasma and blood cells. We already knew that the plasma can improve by just injecting glooth ion but our goal was Can it also improve red blood cells levels? Access if changes in glutathione levels are covered by changes in free radicals. So that was another thing that we want to measure is that what does it do in in one hour? Four hours, three days of using glutathione? Does he have any positive impact to its immune markers? And again, we tried to do a very short study it was a three days 33 day trial only. And we want to show the results in three days. So step one, we will want to recruit all the patients divide them into two groups placebo group, add an active group and make sure that we have all the genders male and female, we had all the age groups from 25 to 65 years of age. And so we want to make sure we have a little bit of diversity in our patient population so that we don’t want to have something somewhat skewed information. Step two was to determine the baseline levels of glutathione free radicals and cytokines and then measure the glutathione levels free radicals cytokines prior What are after the application for hours after applications and three days after applications of literal spray. So it was a very short study. And the reason we did a short time study and not a full six to eight weeks is because in my preliminary work that I did 1015 years ago, I found out that we were able to raise glutathione levels when we applied to the skin within minutes. And so that’s what the trigger was the YT video searches such as short study, we’re going to the whole process of recruiting screening was a 30 patient trial 15 in the placebo arm and 15 in the in the in the active arm. We did all the blood collections we measure Plasma levels of glutathione RBCs PM, the PBMC levels. We also measures the MDA levels glutathione cytokine analysis as well as the mycobacterium infection studies. The microbiome studies was done in vitro as for the request of the IRB, so, again, Design Group 115 healthy adult volunteers. They did get paid 50 bucks just so that they were we were able to make sure that they completed the study. Plus Plus they got the full access of this the complete metabolic panel that they had, and a 30 day supply of the spray after the company the study. So all these people were were active wanted to use blue tide for the future. And so we provided them some some extra price after the study. Second group of the people were again healthy. But again, there was a placebo group and they either receive nanoparticles without glutathione or there are particles with glutathione
23:55
include inclusion criteria was healthy male and female volunteers from 30 to 65. Age exclusion we exclude anybody who had type two diabetes, which was uncontrolled anybody with liver disease, hepatitis COVID-19, HIV AIDS. Anybody had active cancer, tuberculosis history of tuberculosis, you also exclude them alcohol abuse, and that was a definition we went back and forth. But as abuse was defined as that is not the correct answer yet. I believe it was more than three drinks a week is what we thought that we didn’t want those patients because those patients have habitually have low gluten levels to begin with. And so it will skew the numbers for us one way patient they had no allergy to any of the components of gluteal. And anybody who took any gluten products are already adapted supplements were excluded from this subject. And somebody had issues with Q fainting from venipuncture we have extra damage well, so anyway, so we got we had a good healthy individuals, and we were able to do the study, patient screening we had the Western University School campus. The clinic over there did all the initial blood samples for us I believe they had over probably over 60 to 80 patients to get 30 out of it. With said all the testings done at Pomona Valley Hospital laboratory to do assess all the CMP panels HIV happy ANC levels and COVID antigens. We also test for pregnancy I believe anybody that were female to make sure that nobody was pregnant. So this is the procedure. What they did was we will apply them to and here’s the first problem we had. I’m going to lay all the problems while the study was happening as well so you have an understanding of what was going on. They were applying for sprays in the abdomen twice a day. The sprays were the four sprays is equal was theoretically about 100 milligrams of glutathione. And the dose that we’re using was 200 milligrams per cc. And so for sprays it was it was half a CC and they were using it for sprays twice a day or when they sprayed on it was bouncing off a little bit. So the amount that actually got on the skin was less than 100%. And that was one of the drawbacks that we saw that if we had a diff, we would try to change to a dropper bottle, but we had to go back to IRB to get re approval process and the data bank robber thought that let’s not change it. Let’s see what the outcomes are. And we can modify the protocols for our next study if there is going to be a next study. They will done for three consecutive days and pre and post application blood collections were were done. They will all apply on the abdomen on the non hairy area of the body. So the guys, they had the hair were applied on the obliques versus the females. They were applied on the abdomen blood samples that were collected 30 minutes prior to treatment. What are post treatments for our post treatments and surgeries post treatments and the blood sample processing were taken. And we will what we were to measure was plasma RBC and the PBMCs. Again, the blood draw timing it’s pretty self explanatory as to what they were the outcomes expected outcomes, but the proposed theory will provide compelling evidence on whether the external application of glutathione complex literal can improve GSh levels in the blood or not. The second finding will also indicate if altered level of GSh can can cause changes in levels of free radicals because that’s what we want right we we want to improve local levels but does he have any any changes to the pro or anti inflammatory market cytokines in the peripheral blood? And this was the key right? We see this changes in the literature after four to six weeks. But do we see changes in one day one hour or four hours and things like that? So that was the whole purpose of these things? We were we thought it was going to make a change but we were not 100% sure yet. So so that’s what we wanted to study for our protocol. We took blood samples were collected and processed to extract plasma peripheral blood molecular cells and red blood cells, whole blood cultures were created. We’re measuring both the glue tides and the oxidized form of Bluetooth ions in in the samples. We were inoculating the, the blood in vitro with mycobacterium Avium and then the cultures were taken one hours after and 72 hours post infection to assess changes in micro in the bacterial clearance of the host immune cells. Total reduced and access for gluteals were left our measured levels of MDA lipid peroxidation byproducts of oxidative stress in plasma were also measured and plasma cytokines profiles are study participants now I’ll tell you what the most of the most of the study subjects were either professors or students. So either they are in the late 20s, early 30s Or in the 50s and 60s. So we didn’t have anybody in the 35 to 50 kind of rage sort of speak. I don’t think so we had any subject between that age group. So young people are a little bit on the on the 50 plus side. The in vitro infection of the blood culture so this is how they did it. But samples were diluted with rpmi with 5% of our antibody serum to generate blood cultures and blood cultures are infected with in vitro with the process mycobacterium Avium tend to the fifth per well. cultures were treated at watt hours. And so two hours post infection and they do during the terminations in federal blood samples were lysed and withdraw water and the license with little with plated an auger for colonies. So this is the thing so basically, as you can imagine, if it’s a prior to the treatment, the term is prior. Those Those Those should not have any changes. If there’s any change, it should occur. If if it’s a really good it’s one hour, decent for hours and 72 hours so so they were measuring it all the different levels to make sure that there’s any changes on there. So let’s go the results first because this was this was something that we wanted to see. So as you can imagine when they did the 30 minutes before the treatment, there were no changes. Right, the placebo and the gluteal glulam. There’s practically there was no changes whatsoever. One hour after the application of glutathione there were no changes either. So, the bacterium load in vitro did not was affected. The increase in the in the water treatment in the gluteal group is negligible is not significant. But at the four hours at four hours post initial treatment, but this was within four hours of taking glutathione there was a distinctly different reduction in the the gluteal arm when they use glutathione out literal the burden for mycobacterium Avium reduced and this is something that puzzled Dr. Venter drama in his lab. It is lab associates as the hate. They have never seen something that works so fast. It’s it started. They figure this data is not an antibacterial product. So why is it why is it how is it helping reduce the mycobacterium load so fast within four hours. Same thing add on to say two hours or three days of gluten treatment. And this was somewhat the detail was it was statistically significant reduction in the mycobacterium load, so to speak. So anyway, so this was amazing. It’s so even if it’s at one hour, it reduced the load at surgery, it was still reducing the load so it was effective within the first hour of treating treatment with with glutathione. This was something that was very interesting for the for the researcher and immediately after this research they contacted us to see if they would like to their word they are already proposal, a follow up trial in in mice to see if they can replicate the study and see what what is it really true in vivo as well. So we can do animal studies first before we go human trial. So we’ll see how that goes next. This is what we are waiting for is that hey, how does it help increase levels of blue tide in your RBC if that was a big thing. So right away
33:35
this is something that I have noticed personally myself when I first put in for patent application in 2010. That we saw a significant increase of glutathione in RBCs within 15 minutes. When you do the more controlled trial. We saw a similar increase at four hours and 72 hours, both time the levels significantly increased and the levels that were increased for was for reduced form of glutathione and not the total glutathione levels, which is very important to notice because most of the time when you sit when you measure the glutathione levels they’re only measured total glutathione which is the access form of glutathione. What did what Dr. Venkatraman in his lab associate were able to do that well they were able to measure reduced level of glutathione. So within four hours, the levels were increased dramatically at say two hours, the levels are still high up there. So it shows that the upon admission of glug litoral topically, we were able to significantly raise the RBC levels of glutathione immediately. Results of MDA within four hours, the the the load or the add the MD levels reduced in the PBMCs and both from the placebo group to the gluteal group. So it showed immediately that within within four hours we were able to reduce the levels of NAMA Saito cytokines. So this is what the proposal was for. For auto microtrauma he thought that we know glutathione is not an antibacterial product. So that has to be with the cytokines that we’re doing it so of course he was measuring il 12 TNF alpha. I have a gamma, and so and so for il two so the measure all of these things because what what they were hoping for is that she’d have alpha activations was actually improved macrophage activity to control the mycobacterium Avium. And sure enough, within 72 hours, this is the levels of il 12 and TNF alpha. It was significant more than doubled, more than doubled the levels of of interleukin 12 The TNF alpha dwarfs and significantly increased over 30% increase of levels of TNF alpha il twos. Again, I’ll twos were more than doubled also within within three days. And the IFF gamma was also improved more than more than doubled within within the same timeframe as well. So this is this was something that was very interesting to notice that how how fast we can improve those markers in my clinical applications. I have patients that have used the product and within within hours they have come back and told us that the pain has gone away in the knees or the joints or whatever that is right. And I’m not sure the pain is coming from but to reduce the inflammatory markers or to help help with inflammation immediately. We have noticed in the cricket practice numerous times that the patients have told us anyways, so the results study reported no side effects. And even though the it was a very small population, they didn’t see any side effects, but in the larger populations that I’ve been using for last 15 plus years. The only side effects that I have seen with this product if you use for repeated use for long periods of time is a rash and the rash is dose dependent as well as time depends so the longer you use and the dose is too high. The body tends to have a mild rash which usually goes away within within a few hours once you stopped using the product, but in the smallest study sample there was no side effects there was observed that they had an enhanced immune response. And what they saw was because of that they were able to see the mycobacterium Cfu Campbell significant reduce from the good growth and treatment group after four hours as low as 22 hours. They also saw elevated levels of reduce for glutathione in both in in RBCs at 72 hours. They also saw decreased levels of MDA at four hours and 72 hours post initial global treatment. And the best part was the increased levels of il 12 il two TNF alpha I’ve done gamma in plasma and so two hours post glue treatment. This is something that has triggered another trial that he wants to Dr. Renko travel wants to do, and he’s already pre the IRB application right now is to see how we can improve if I can improve in February markets like this is going to help with diabetes is going to help with arthritis. So anyways, so those are right now in IRB right I’m looking for that part and see if we can get some approval and we can probably start Destiny next. The benefit of glutathione topically guess what it is? It’s not invasive. It’s a lot of ambition is so easy to just apply topically. Zero side effects in a smaller group compared to oral has GI distress or IV has rash issues. IV is usually a very high dose. And so sometimes you get a rash with with high dose of glutathione and enhance immune response resulting in a reduction in the bioburden. For microbiome ABB even though it’s in vitro, it shows promise that there may be a potential of of helping patients with with compromised immune system which is the number one cause of death is mycobacterium. And so hopefully that can we might be able to help people with their immunocompromised, increased levels of glutathione increased levels of glutathione also increased levels of cytokines il two il 12, TNF alpha and so on so forth. And decrease of MDA. I mean, it’s a very short study, if we can show this thing within within four hours to 12 hours or 32 hours. Imagine your repeated use of this product over a few birds. What can trigger for us so this is what it this is what so promising for us. So, in summary, the results are pretty easy. Satisfactory. I think we already talked about this one. I do want to acknowledge all the team that has worked on this thing that the regular amateur is lab members, Cavan and Melissa RB Logan Nissar, James auvik, sloth, Brianna, for processing on the samples. We do want to make sure that it is that this is a chihuahua that Ray Tawny and Dr. Venket Rob and their support. We can’t forget the grant money that they receive from from both them or pharmaceuticals as well as NIH to support this thing. Because we we need we need people we need funding to so that we can break we can keep on doing this work. For to make our life as a clinician is better for the future because as a pharmacist, I see so many prescriptions that I fill every single day with no promise of patients getting any better. I would love to have offered something that that we can hang our hat on that day. Hey we help this patient not just improve the markers but to make them feel better without having any side effects. That’s That’s my ultimate goal. And I want to make sure that if he has any was interested, I want you to have this slide ready for you because use the code webinar 14. Go to the practitioner page sign up. We have a special price for you today. And just for today’s there’s no minimum orders for quantity, interviewed trial. If you want to try one product for yourself. I would like for you to at least use this code to get a discounted price to to use this product. Enjoy enjoy the benefits of glutathione in a very fast pace. And that’s what that’s what we try to do right now is see what we can do to do. We can help every individual out there. So with that, I’d like to open up things for q&a. I like to answer all the questions for anybody that have. So if you can put in the chat box or just raise your hand and I can then you can unmute yourself and just go from there. So I do have one question right now. Is the rash caused directly by inflammatory cytokine? Maybe? So, yes, and no. There’s two parts of the rash that I’ve been dealing with the rash for the last 12 plus years that I’ve known off. And there’s two theories that I have as of right now and I could be wrong on either one of them or both of them but I have some very to a to one of the
42:56
excess production of nitric oxide. And we have done that we have done the saliva testings with before and after the glue without application. And we see the color changes show you the increased levels of nitric oxide production. After using a glue file. That could be one of the reasons why we have accidentally oxide production giving you rash at the injection site at the application site. The other one that we are seeing is also the the the the effect how fast the growth is getting absorbed. And maybe it’s causing a Herxheimer reactions that that we normally would not see it on a on a slow application or slow absorption of glutathione. So those are the two reasons I think that the rash is there, but the rash dissipates. Really fast once you stop it within hours and it once it dissipates. If you reduce the dose down to half and then slowly go up again. Then the rash is gone. Alright, so second question. I love to participate in animal studies. I will integrate medicine. Please if anybody wants to participate, email me directly. I would love to put you in touch with the university. We do have a veterinary school at Western University. Wanted to to to animal trials right now. Because dogs have the worst case of HIPAA, HIPAA toxicity because liver liver is one of the cause of death most of the dogs and feline cats, but there’s a epidemic of shingles are or herpes in in, in feline cats. And the human society would love to find a solution where they don’t have to put all these cats down and so they will do those trials. I believe we both will be effective. And so if you will get in touch with me please email me directly at Nyan at Central drugs are x.com and I will credit you guys with the university who’s in the trials. Is this smell to the trouble solutions? Yes, there is. Gluten if it doesn’t smell it’s not working for you. That’s that’s where I look at it but yeah the distinct odor of glutathione is there the software is there the file group has a smell to it. But the other thing is which is even even more subtle is beta cyclodextrin that is bases used as as a carrier is also very sticky and tacky. So when your private growth on your on your abdomen or your arms or your face or wherever the it has a distinct odor but it’s going to be very sticky. But if you just keep rubbing it on the smell and the tackiness dissipates in about two minutes, you just have to keep on rubbing it on until everything is gone takes about about a minute or two minutes maximum. So yes even though the smell is there, it should it should dissipate pretty fast. digital presence study to sublingual, we have not done a compressive study with either sublingual or liposomal technology or IV is because if you just go if you just go on clinical trials.gov and just type in glutathione I just did just recently right right before this presentation today, and just in United States there were 140 clinical trials there have been registered in the last few years. Okay, and they’ve all been using either nasal form of nasal spray of glutathione or liposomal form of glutathione or capsules of glutathione and none of them the absorption of glutathione is there right away. What that tells me us tells us that the gluten is getting broken down into various amino acids. The amino acids are getting absorbed very readily in the amino acids is what’s been utilized to produce glutathione again, and so I would I would probably do a different trial if to prove that hypothesis is that we should do a study of glutathione and amino acids and see which one has better results or is it the same results. And I think what what you’re going to find out is you’re probably going to have the same results over time. Using amino acids and glutathione by itself separately. Duty to perform GS experience blood test freezing literal, not that I know off. I believe G six PT is is something that you do measure if you’re using vitamin C all the time, but when you blurt out I have not come across anybody that has any issues when they use glutathione with G six B deficiency so our answer would be no. Do I need to clarify that? I probably do. But I think the answer is no as of right now that I know of. Did you mention a need for an IRB? Yes, we did. Did we have to do the IRB because we weren’t able to do human trials. And initial work that I did. I did I did do human trials but I don’t do one patient at a time and one patient time you cannot get data significant data that that’s going to be reproducible. So we had to go to IRB to get to get our 30 patient trials done. So that’s what we did. IRB do and would you have any interest in making Research International if you’re legit IRB? Absolutely. In fact, I have. I have two meetings just this week alone. I live two different institution right now this week to see if they will do some human trials. We have one one person, another university in San Diego wants to do a trial or dash and then we have another trial for Parkinson’s. So we are we are we are working with anybody and everybody that would love to there was through trial and once you get that get the work published. We are all ears right now because very so seldom we find a molecule that is that has such a profound impact so fast or body that the faster we do some human trials that we can do, the faster we can get to the public and enjoy the benefits of the product. And if it’s not good, then we need to move on to something else in our life and not to keep on bringing up again the same product over and over again. So yes, I am interested. Also, can you compound? Can you comment on the use of Blue Diamond and missing high dose vitamin C? Okay. So I’m gonna give you a bias of a vitamin C and glutathione. And as this is purely as a chemist, okay, as a pharmacist, I look at a chemical and vitamin C. It’s supposed to be the antioxidant. But I by all means, if you look at the chemical structure and what Vitamin C is all about, it’s a pro oxidant to begin with. It is not an antioxidant at the low dose vitamin C. What it actually does, it provides the energy to regenerate oxidized glutathione the G SSG molecule in our blood requires energy and it gets energy from either vitamin C or sunlight or vitamin E or something or getting energy and basically, it becomes GSh again, so that’s why vitamin C at low dose is an antioxidant. And I believe it’s because it’s regenerating glutathione because after that it becomes a pro oxidant I don’t think so vitamin C has a redox properties that they can become a pro acid no doubt them at different concentrations. But I think that at low dose it is regering glutathione. I have so far not been able able to find any research or doubt yet but this is this is what my theory is at this point. Have you demonstrated an increase in those inflammatory markers without inoculations with bacteria? Oh, by the way, yes. So so the inflammatory markers were were done separately, though, that was in vivo study. The in vitro study was only measuring the the bacterial load. So the the, the inflammatory markers were actually done in vivo. So they were they were the bloods were drawn after after after the other after the treatment was over. And then they put all these various test tubes and they’ve basically inoculated with some mycobacterium in for in vitro studies, but then the biomarkers or the inflammatory markers were tested. Actually in human subjects. So yep.
51:56
Please put a direct link in the chat. Oh, thank you Dr. Clearfield for putting my web for my email address. Thank you. Follow up on comparison, then why not test levels beyond say two hours? Okay. So what happens is that of a goal was to show that we can improve your glutathione levels immediately. In my previous study that I did back in 2010 2011, what we found out was the glitter is a very short half life. So the glutathione levels rise up and Bates basically gets out within 12 to 14 hours. So our goal was to make sure that if I do if I do give glutathione does it does it improve the levels immediately and once the loved ones the levels improved? I want to see that hey, if it three days of continuous application is the level stays the same? Are the levels still stable? And the answer was yes. If it’s true for 72 hours, it can be true for a year from today. And so the reason we did our due pass her two hours because because again the theory was within 72 hours, we were able to improve all the markers that we think are going to be influential for for inflammation for for the bacteria and for the for the for the for just for trying to figure out what the dose is going to be. Now I agree with you that if you want to see a positive impact for for gluten levels in the brain, substantia nigra, but that’s that’s the next study that I’m working on right up at the University of Pittsburgh is what we’ll do is we will improve the gluten levels in subsection DiGRA and we can do that there’s a possibility of reversing dementia. Parkinson’s can get can be used as an adjunct to Parkinson’s disease or as a prevention. We don’t know where where this is going to lead to us for next research. But our first goal was to prove this and then from there on we can get bigger funding to go for the four more mainstream trials. The one that we’re talking to the San Diego University is basically the whole thing is funded by NIH. So the so this will be a good trial for us to be involved with because the money is coming from NIH to do this trial. So bigger trouser means a lot of money. And as a small pharmacy myself, it’s really hard to to justify all the costs that it takes to get all these trials done by myself. How does it compare to IV glutathione. So there was only one study that I found out about IV glutathione back in 1991 is what they found out was that they were given two grams of bolus IV glutathione 100% of the gluta was ended up in the plasma and nothing was in the red blood cells and so within 14 minutes, 14.1 minutes to be exact. All the gluten was was concentrated in the bladder and we basically were able to you’re able to get rid of it. But there was one caveat. What happened was that even though there was a 300 fold increase of gluten in the bladder there was only 10 fold increase of site cysteine in the bladder. What me what that meant was gluten was getting converted into various amino acids, and cysteine was getting reuptake or reabsorbed in the bloodstream, which which which was the reason why we saw sustained effect of, of glutathione Ryza growth at levels I will have to a couple of days after the treatments of IV because the system was was was was getting absorbed, reabsorb and blow that was was being produced based on that. So So IV gluten is is not a bad thing, but it’s it doesn’t the cost is does not justify why we should be doing IV treatments if the topical versions can give the levels to you immediately within four hours. Dr. Gerber, do you do like liposomal glutathione again, Dr. Venkat Raman in his lab worked with liposomal glutathione for 15 years, absolutely fascinated by this product. In fact, I worked liposomal technology back in 2002 2003 when there was no liposomal price out of the market at that time vitamin C glue tired and everything I did not see a clinical outcomes that I want to see in my patients. So I did not like the liposomal it’s for that very reason. But does it improve blood levels? Yes, it does. Does it? Does it improve right away? No, it takes four to six weeks, but the four to six weeks it will raise the levels up which tells me that it may not be the glutathione itself. It may be the amino acids that the Buddha is getting broken down into that again that there is going to reabsorb to make glutathione again and again that’s that’s just a theory but that that was the theory was put to test by Texas University in 2010. And they did a 13 patient trial. These are autistic kids. And they were given liposomal form of glutathione as well as oral capsule glutathione and they were saw zero increase in the red blood cells. What they saw was the increase of all the amino acids inside the blood. So which tells us that yes, the glucose levels will rise eventually was the amino acids are reabsorbed in the body is using using the symbiosis to produce glutathione again. So that is the other thing that we have noticed. So do central nervous system cells have interested in glutathione increase on use. This we have not tested yet and that is there is something that I would love to test out. So one thing we do have noticed as the post COVID brain fog is getting that re re Uteri that did all the work on glue glue on COVID patients he’s been using for over two and a half three years now. Almost clitoral plus for post COVID long horror brain fog patients and the brain fog is clear been five days or less. And so he’s thought that hey, this is this is reaching CNS levels of glutathione. But the flip side, it may not be true either because the brain fog could be an inflammatory response. And so maybe the information is coming down to the brain fog is going away. Regardless, there is there’s researcher at the University of Pittsburgh Dr. Provided Dr. Joseph maroon, they’re actually doing brain scans spectacular brain scans to measure glutathione levels, and I’ve sent some samples out of them already and I’m just waiting to see the results from that. And if I can if they can, if they see a spike in the in the brain activity or brain levels of glutathione this will trigger research immediately. So as of right now the answer I do not know I do not know. Do you have experience with using glue for autoimmunity? Yes, plenty of it. The simple the one the best example I have is my dad. My dad is 87 years old today. He had arthritis he had type two diabetes in his late 40s early 50s. He developed blood pressure and in late 50s He got arthritis. He’s at 70 years old today. He is no longer diabetic. He no longer has blood pressure. But best of all, he is no longer as arthritis. He walked six miles a day it works perfectly fine. It has no issues whatsoever. His all arthritis injury that the bone deformation. He had a bone to add here that knee replacement done. And it’s like it’s it’s like a brand new person today with no pain, no inflammation anywhere in the body. That’s just one one thing. We have few doctors that have use of folliculitis we have paid artists have used for the personal use for psoriasis and things so we’re gonna try this and seen some tremendous results with that when the results are not immediate. Of you’re talking about four to six weeks to see the initial onset of of reduction in the symptoms. But after that, it’s like it’s like day every day goes by the getting better and better and better. So quite a few results we have but at the same time if you use a product and if you don’t see results that you’re looking for. This one has 100% money back guarantee no questions asked. Because I want people to try the product. If it doesn’t work out after using the product. There is no harm no foul the fully refund product. There is no shipping cost to so there’s like there’s there’s no cost to them. There’s no obligation for the patient. So that’s why we have a lot of patients try out for all kinds of diseases. And that only thing we asked was refund the money. And then we asked what do you use it for? And what were the outcomes and that’s what we found out about other things. Is the RV part of the university? Yes, it is. Unfortunately, the university has their own IRB and so that’s why I only work with the universities because they have their own IRB and they they use their own team to do that. Now. Can you collaborate with them? Absolutely. The answer is yes. It’s just that you you need to have the university professors be on the research team as you do. So and you can have a collaboration with them outside. It’s a little trickier but still doable. Why do some patients who who prescribe IV glutathione get nausea and very thirsty? Woof
1:01:49
I don’t know. I don’t know. I I’ve used growth on IV for probably close to 19 years I was I was making IV growth I’d at Central drugs for until tonight. 2019 And we saw very minimal side effects very minimal. Nausea was was probably the symptoms of of higher infusion rate than the gluteal itself is what I think for it, but thirsty I do not know I do not know I’m sorry. I don’t have an answer for that one yet.
Bill Clearfield 1:02:20
We used it. We’ve used it for Parkinson’s patients 1500 to 2000 1000 milligrams and actually in a push and a 10 minute push and it works quite well. It’s for spasms and the tremors at all. The real problem is that it only lasts and doesn’t last 72 hours. So you have to keep renewing it every day. So have you had Have you had any success with those types of patients with the transdermal?
1:02:53
I could not say yes 100% Because we have very few Parkinson’s patients right now. And what we are what these do see is the the range of motion is increasing. Is a tremor decreasing, and I don’t think so, but most of the patients that we have on Parkinson’s patients they are feeling energetic their range of motion. They feel better, but is not getting to the disease. Right before this call. I did reach out to Michael J Fox Foundation in fact, because they they are out funding all research on Bluetooth on for Parkinson’s, so we just I just sent an email out right before this meeting. today to see if they would like to fund with one of the doctors I’m working with.
Bill Clearfield 1:03:40
So Dr. Dr. Perlmutter had a whole series on you know, actually I think it’s on YouTube their videos it is
1:03:49
using 3.8 grams of IV power. So which is I’m using it and it works by the way it does work. So it’s just matter of trying to figure out at what dose of topical, can I get that level that is required to cross the blood brain barrier. And if that crosses the blood brain barrier, and how long does it sustain? There’s a lot of unanswered questions as of right now, unfortunately. Okay, what is this next question? Any opinion on ImmunoCAP platinum from the new tech, even a Cal platinum is a cysteine product and is great because it just gives you assisting molecule that’s going to polish the reuptake and polish growth and from there, it’s a great product, but it’s all these products are good, but you’re depending on your body’s ability to produce glutathione and there are a few people that have enzyme defect that cannot produce glutathione and then the Nautilus project actually works. Do antihistamines help by skin reactions by clitoral? Actually no it’s not a it is not it is not a it’s not a histamine release issue. What what I what really works is you put a lotion over it over the rash, any lotion and the rash just kind of goes away. So I don’t think you need antihistamines. I just put people to just put your favorite body lotions over and that they okay. How about patients with a first year from possible years of high blood pressure and poor lifestyles? I don’t have an answer for that one either. Marry ik if you email me directly, I’ll try to figure out some research on that one. And I’ll get back with you on that as well. I’m sorry, I don’t have any answer for that one. What is contraindication so I don’t do there is any contraindication as of yet, but there’s one group of people that’s out there that has called me out and I don’t have all the answers that are down yet is somebody has a GGT enzyme trans a transfer enzyme defect, and they have cancer. You cannot use glutathione on those patients. It’s a very small subset of cancer patients. And it’s it’s something that there’s a group at the UK that they call me out on that one. And I don’t know all the answers yet, but I’m just disclosing this information out because I would have loved to learn more about it if possible. And see if this was true or not. And if it’s true, then I want to make sure that I tell everybody not to use the product at all if you have cancer and if you do not know if you have the enzyme defect or not. But other than that we have used in cancer patients all the time in fact, with great success with good energy, the Caxias kind of Gods of people like eating better foods and things like that. So it’s overall very, very positive things. So don’t use gluta with vitamin C since they negative each other in relation to toxins and toxins. In fact so he had not an REO. So so in our glue that topical product we use little bit of vitamin C. And the reason we we use little vitamin C inside because a lot of vitamin C is actually giving enough energy to keep on to keep on making sure that the water doesn’t get oxidized. And so I use low dose vitamin C all the time. So even if on my patients I tell them if you’re going to use Vitamin C use low dose one gram a day is plenty. If using topical the glitter already has fallen because of vitamin C ins there is plenty. So that’s all I need. So what even see their low dose, but at high dose. You’re right it can negate the effects of glutathione as well. What clinical responses have you seen in Parkinson’s only click response our scene is better movement better energy. The tremors have not reduced, stopping and stop and go for the motion has not reduced. The number of patients that have that have used Parkinson’s are very, very small. I would say less than 100. And so that’s the reason why we don’t have much data on it. We have 1000s of patients using this product on a monthly basis. But the number of participations is very, very small. Happy birthday. My dad is 87 He just turned 37 in February 11 and I mean this when at the age of 84 hit a double knee replacement and he was out of the hospital in a day and a half walking on his own. And so the hospital in Orange County put a T shirt over the Superman shirt on him. I said this is amazing. I’ve never seen somebody with double replacement walk out of hospital in day and a half and in literally within within two months. Three and a half months after that he was traveling the world. He went to MD after that and everywhere else so is really good. Do you use go down for Hashimotos? The answer is absolutely yes. But not all Hashimotos are are secondary to via if the hash was secondary viral infections. Yes, it works really good if it’s secondary to some sort of pain or toxicities yes and no right? But because not all metals can be killed by by glutathione. Mercury. Yes, but not all of them. Maybe not iodine. So Hashimotos. It has worked on a lot of stuff they don’t see. But I’m sorry, but not but not all of them. So I just want to make sure that if you want to use for Hashimotos use it for 30 days, you should get the results immediately if you don’t get the results that no you don’t have to buy it again, or ask for a refund or an issue to reconsider sulfur allergies. So gluten has no sulfur in there, the Theil group that assists team group The smell is coming from the file group. It’s not a sulfa allergy. So in fact, my family member has a sulfa allergies and she uses growth on every single day. No problem whatsoever. So I don’t see sulfur allergy as deterred from using clitoral product. What ends up defect again GGT glutathione budgets are GST, GST growth and as transfers enzyme added my time is up I’ve read fewer questions sorry. How long have you been using the products and participations three and a half years. My first patient was from the university. He was a state Medicaid program. He couldn’t afford anything. So he will so the doctor put him on a three month trial. He saw the benefits of it. So since then he’s been buying the product from us. After that three, three and a half years ago. We have put on other than it her patients on the on the Parkinson’s, but I’m not getting convincing data back. Usually when when people see the results. They call me the day, the second day, the next month immediately. I said oh my god, you changed my life. But I got that from Parkinson’s patients yet so that tells me that I have seen I have some more work to do. given intravenously is great by cancer. Weidler is currently but cancer. I’m not sure I noticed I’d say the glue is due to its contract indicating cancer. What I’m seeing is that I saw I want to one group or the UK has called me out that gluten should not be used in all cancer patients, especially if they have the enzyme defect. Because if then the GST enzyme defect glutathione can actually become harmful to them. It doesn’t matter if it’s IV or glittery or liposomal or whatever. And again, that is something that has been called up I have nothing to back it up as of yet. But I’ve always studied that other things I’ve researched. I cannot conclusively say that is true but I just put it out there that if using cancer patients that’s just exerted caution, caution for the first 30 days make sure there’s no issues and then you can use it after that no problem. I mean, I have a few family members in the Deaf cancers and they’ve been using it with surprisingly good success in the sense that their energy levels are high. If they’re eating healthy, they they just have a full life in front of them as of right now is a cancer gone completely and now it’s not. Alright.
1:12:40
I’ll give you one anecdote. So I met you in December at a firm A long time ago. And I told you about this pediatric case I had a four year old girl with some idiopathic liver fibrosis chronically elevated LFTs and so forth. So I did the trial for her and I figure it’s a perfect product for four year old because you apply it topically no issue with this. And it went pretty well. She was doing it fine for three four weeks, but she developed a contact dermatitis and we had to discontinue use unfortunately but we did get some blood work done, but unfortunately we didn’t see much change in the LFTs at all. They’re still elevated, elevated ALC FOSS up to 350s and the ASD ll T are still like 5136
1:13:23
Yeah, it’s we have seen I don’t think so we have many failed cases where they have high ELT ASD levels. So for everybody that we have treated, we have seen tremendous results in bring the levels down. It takes anywhere from three to four months to do that part. So you’re right 30 days may be too short. Plus four year old I’ve not done a four year old patients. I’m not even sure what dose they would require either. Do we treat them as an adult dose or pediatric dose? I have no idea. Yeah,
1:13:55
I didn’t want to spray
1:13:57
once 25 milligrams probably not enough. Yeah, because in the adult we will we will be using for spreads which is 100 milligrams, B ID twice a day. And the results were we saw the results in about three months.
1:14:12
She’s a very petite girl. She’s a lean probably like 36 pounds very light.
1:14:18
Plus one spray should she should not get any rash from a glutathione either. So the worst company doesn’t work. The best thing is that it did not. It did not give any any side effects. Yeah. Oh, the couple more question came in. What do you suggest testing for the ends up before us? That’s what the data is. I tell the doctor to do the tests for the GST enzyme. And if they had the defect then then you have a choice to make give good or not to get tired. But yeah, I don’t know who does the testings either. I talked to doctors data lab, but I’m not sure that they’re doing the tests either. So therapy has to continue forward like your father continues to take it all. Okay, so my father has been using it for nine years. He’s my patient number one. He’s been the longest person who has been using this product in the world, right. So everybody else has been using for three to five years maximum except for my dad and my partner in crime. My scientist that works with me over here. He’s he’s in his mid 60s as well. He’s the border we’re using for eight, nine years together. My partner in crime PhD, he doesn’t have blood pressure issues anymore. My dad is, you know his story. If you read my book, My history is in my book because it is absolutely amazing. The only regret he has is he only has three friends that are still alive today. And that’s a little red he has because nobody believed in him. And nobody else took a product like he did. And so he sees his people, his friends kind of passing on or are not doing so great. So, if you live if you love your friends, please do what you do but keep your friends. Make sure the friends are healthy as well so that you can have somebody to live with after when you’re 87 years of age. But yeah, continue every single day, short half life so you can you can pretty much take every single day. One thing that I do notice in my dad is that he doesn’t take it twice a day every day anymore. He only does it once a day and his levels of growth are still across 1000 Micro moles per liter. That means I figured out that your body recycles glutathione after after so many months or years of application. So you might be able to just use it once a day and still be okay. So, just just something that I’ve noticed did he change his diet or just literal? Yes, so he’s diabetic. So when he found out that he’s no longer diabetic, his diet did change his loss of sugar now. He started drinking wine at the age of 85 for the first time, so every weekend now he waits for me to come home so you can open a bottle of wine with him and things like that. So his diet has changed a little bit. He’s no, unfortunately that the issue I have with my product is that I did not anticipate the costs it was going to meet for for me to make it there’s not enough margin for me to give 27% to full scrip. Unfortunately, I’d rather get a discount to the physicians and to get discounts for scripts so nope, whatever you need, you can deal with us directly we’ll ship it to you. Or do a Jackie or Maria they will be able to help you out with it. And we will take care of you. So unfortunately I’m sorry we don’t have on full script a whole superhero thing as like that. The cost of the product. It’s the retail price is 124 glutamyl and one and to her for glitter plus, and the wholesale price is as low as about half of that 100 bucks for Google Plus and 6250 for the for the literal. Again, there’s a tier pricing discounts but if you have five or 10 patients a month, you can bet you can get the lowest price possible. If you just want to try the product use the discount code the webinar 14 today and you can try the product at a discounted price for just one product also. How long will you last average? It’s if you use for sprays be it twice in the last 30 days. The which is pretty much all the protocols that are out there is always B ID. Very seldom you may have to use it every four hours. And there is if there is if you have an acute infection because as I said it takes four hours to bump up the level. So if you keep on using every four hours for maybe a day or two of the 48 hours, you can literally you can control the infection way back down onto the bike takes over and then you can go back to just using twice a day only.
Bill Clearfield 1:19:09
Can you put the the the code
1:19:13
out I would love for people to just take a picture of it. Oh what happened to the thing? And let’s see. There you go. Is practice webinar 14 or scan this thing and it will go straight to the counter and open up the counter day. If you’d like to talk to a salesperson which we don’t have too many, but we have some great people that will help to support you with any questions. If you if you have any, any particular conditions that you’ve been working with, I can I can give some anecdotes on what I have seen. If you’re interested in doing some clinical trials and want to partner with somebody will love to learn I’ll encourage you to contact me directly because the more we do some studies the more information we can get out to the people
Bill Clearfield 1:20:11
here’s a question about physician account or do I need to stock it? Can patients order it from a website?
1:20:19
Both both. You can either start getting your office and resell them, or you can send to the website directly and you still get a percentage coming back to you. Because we want to be we want to support all physicians. We as a writer we only have I think two physicians that are donating all the money that the commission to one doctor is doing everything to the Wounded Warrior Project in another doctor is doing to some some kids foundation, but But regardless, the money leaves my pocket for sure it comes to you or to anybody that you want assigned to you.
Bill Clearfield 1:20:59
Well yeah, well you have your slides up Dr. Patel, can you go back to the cytokine
1:21:03
studies there?
Bill Clearfield 1:21:07
Because maybe I’m looking at it backwards, but is the gluta role increasing the cytokines?
1:21:15
Yeah, these are these are pro inflammatory anti inflammatory markers, right?
Bill Clearfield 1:21:20
Yeah. What are their inflammatory markers, not anti inflammatory markers.
1:21:28
I might
Bill Clearfield 1:21:28
my might do I have it backwards. I thought interleukin four and 10 were the anti inflammatory cytokines.
1:21:37
Let’s see.
1:21:46
So TNF alpha is the is the one that’s actually the macrophages to basically help the the pro inflammatory markers. Yes. Okay. The point of this or the point February markers are being activated to help with the macrophage activity. I believe that’s the reason why it’s also helping with viral infections also. Because as much as we know we don’t know how to kill viruses, and we’re hoping to the macrophages is doing the work for us. Okay, so these are the
Bill Clearfield 1:22:21
so I don’t know maybe I’m, maybe I’m looking at it backwards. But shouldn’t this be the post and shouldn’t the blue be the post and the red be the before
1:22:33
I wrote about how to find out for you? That’s a clear. I’ll get back with you tomorrow. I’ll even have to record Rama right now.
Bill Clearfield 1:22:42
Am I reading it wrong?
1:22:44
I just got a slice this morning from him. So I’m not paying attention to it. Because the slides I had from a week ago has already changed because as the data keeps on coming in this this is the last data slide. So now it’s done. So I will I will get Dr. Venkatraman
1:23:04
inflammatory markers,
Bill Clearfield 1:23:05
I think you want those levels to go down. Not up.
1:23:09
I’ll get back with you tomorrow morning. Okay, hopefully he calls me up tonight or tomorrow morning. First thing that I’ll let you know right away. Okay.
Bill Clearfield 1:23:19
Okay. Anybody else have any comments, questions? You got the put that put the little barcode up there again. Yeah, we’ve used some of it. We really liked it a lot. So thank you. Yeah, and webinar 14 at checkout to receive
1:23:44
this little bit of pricing discount. I just want to make sure that we help everybody. And it either concerns questions just let me know directly.
Bill Clearfield 1:23:57
I can from experience Dr. Patel is very open. He’ll he’ll ask answer your question answer questions about just about anything in our field. And he’s very knowledgeable. He’s, and he’s a good guy too.
1:24:10
Oh, thank you. Appreciate that.
Bill Clearfield 1:24:13
And then just to let our folks know, you guys put out a lot of literature that is very good for patients on hormone replacement and you know, all of those sorts of specialty things that you compound. I mean, it’s really it’s very down to earth understandable. It’s not you know, Dr. Language, and very colorful. I mean, you know, we pass them out all the time we use it, we use it a lot. We lose a lot of your lot of your literature. So twice
1:24:41
a month we will be only two twice a month and something educational. Once in a while to the my team gets liberated and see and put some marketing material out there. But typically, it’s always educational.
Bill Clearfield 1:24:55
Very, very good. The one on and Clomiphene was good and while ago you get one on one, low dose Naltrexone LDN. One page, you know, sort of you know, highlights so that’s right. If anybody needs any of that kind of literature, you know, please get in touch with them. They’re really, really terrific about it. So
1:25:17
yeah, just sign up on my website for my newsletter and we will ship it out to you once or twice a month.
Bill Clearfield 1:25:27
Okay, hold on. Okay. Okay. So, any other questions?
1:25:36
Excellent talk.
1:25:38
What conditions are you using it for?
1:25:41
Me personally?
Bill Clearfield 1:25:43
Yes, you personally.
1:25:45
Oh, so for me personally, I use it every day. Again, just just for so. I like to drink alcohol at least once a week. And, and so alcohol dehydrated enzymes activity is is activated by glutathione I will you’ll never see me even buzzed or drunk ever. I don’t know it’s some of the things that are good that will will will just pass is really really fast. So that’s my my personal bias. Because if I may drink with my dad, I would like to be in sober condition at all times. While other than that is my thing is that my lifestyle is so erratic I’m always running 10 different directions. So I like to keep my my my antioxidant effects highest all the time. So I use it once or twice a day where if I remember if I remember once I do hyperbaric chambers have before they refer the chamber out getting up put some growth out before I go inside the chamber. Things like that. But that’s what I use it for. Other than that, I don’t have any conditions personally myself but so I don’t need I don’t need nothing for the hour. But for my patients for my for my kids, they use it for by my daughter, she’s a for acne all the time. But if she has no active then she I’ll tell not to use it ever. My son who is prone to headaches all the time, and he used to go down to basically reduce his headaches down. My other daughter she does she never uses it up. Quite a thing.
1:27:21
Question about migraine and headache. How does it help just for the hearing?
1:27:28
It’s not for all the magnetics My wife has migraines all the time. And she uses that twice a day. He doesn’t do anything for her. My son has headaches, and for him he’s just bloated and it really helps him out a little bit. So I have absolutely zero idea how it’s helping him and not my wife. My wife, I think is hormonal headaches. So maybe that’s the reason but again, I’m not a headache expert at all. So by all means I have absolutely zero idea about headaches
1:27:55
and answer controversies so you said it is safe in cancer. I I really like to have some articles suggesting that it is safe for cancer. So
1:28:10
the if you just Google if you just go to PubMed, there are a few articles on cancer therapies. And if we look at the cancer therapy, the cancer cells survives on glutathione. But they only survive on endogenous production of glutathione. So they hydrate the mitochondria and they basically take that endogenous production of glutathione. That’s what it survives on. What happens is when you give exogenous glooth ion, when you give exogenous form of glutathione, the endogenous pressures shuts down completely. So in theory, what you’re really doing is you’re depriving the cancer cells have glucose in the blood from the endogenous sources. Now to absorb that external sources, I have no idea. But in theory, it sounds good that at least you’re depriving cancer cells of hijacking your mitochondria for the for the growth outsources it again, that’s the theory. That’s what the research is telling us right now. But there’s no proven facts along those lines.
Bill Clearfield 1:29:17
So what do you see as your best your best sellers doctor Dr. Patel, what so what are the most common common entities? You know, oh, this is well, that it’s used for
1:29:30
so i The most commonly I have all my type of diabetic patients have a high triglyceride patients. elevated liver enzymes patients, people that at least have to have drinks two to three times a week. People that are with aches and pains, inflammation. These are most of the patients on line these. I have a lot of former skin conditions. I have melasma patients I have skin condition patients, live respond patients. So things like that. The last few years we have a lot of longer COPD patients, which is either either they had COVID issues of vaccine issues, and these are all pro inflammatory markers that have been activated. And so they’ve been using blowdown to help without those kinds of symptoms. But that’s what we are seeing all the time. And the number of products sold is still clitoral, not the plus not the plus. The plus is all my high end clientele. I have a lot of athletes, Olympic athletes, NFL athletes. I have a lot of very high net worth individuals that want to have expensive products. And so I get them expensive products because it’s not that it’s going to be better for them. It’s just I tell them to use their cheaper product. But now I said Hey, is it gonna be big? Is it gonna be detrimental to me? I said no, it’s just costing too much money for no reason. At all. I got plenty of money. And so there they were using the expensive product. It’s not necessary, because you can get your blood levels, even with regular literal, you don’t have to go to the plus. So anyway, that’s that’s what we see.
1:31:10
How does it work for melasma?
1:31:14
So melasma it is. Okay, so for melasma I’m working with I’m working with physicians to basically fix the adrenal glands, and once the adrenal glands with the hormone replacement therapy, once that is in proper shape, we add the glutathione to the whole regiment to help with with the even though even the evening of the turnout, so we have no choice up in Montecito California. And she’s been using this a lot of policies have a lot of patience because she doesn’t need a lot of patience. But she’s been using for glitter glitter for all the patients for melasma. But she also does. She also refers the patients to a hormone specialist to deal with the hormones first, especially the adrenals. And so we give them some chromium picolinate to reduce the carbon sugar cravings, rebuild adrenals give them some vitamin C and some adrenal rebuilders to do that part, and then we add the glutathione or the whole regimen. How is it helping them I’m assuming that it’s evening the tone out I’m not sure if it’s, if it’s if it’s doing anything more than that, but the liver spots and the eight spots are gone because it really helps the liver function better to glue the glue down it does. And so those parts of God within 30 days, the melasma takes six months to nine months sometimes.
Bill Clearfield 1:32:39
You spray it right on the little skin lesions or
1:32:42
you don’t have to you can apply it to your TV and it still get rid of it. But if you apply on the face directly it has other benefits too because of we’ve we’ve done a clinical trials for for cosmetic reasons. And we did 15 markers, and 50 or 50 markers had a positive outcomes over 80% which is the company that do the clinical trial for us they were shocked to see a product that is that has 100% success in all patients, which was the gluteal we use a different name for that one. We use a product called G Gee it’s a different day for the cosmetic side but it’s the same product a pretty much
Bill Clearfield 1:33:25
there’s a question about the shelf life. Did you answer that? Well, you
1:33:28
know I do so shelf life increases as the concentration increases. So the glitter is about 18 months. The grip plus is about 24 months. And we do have another couple more products which are not releasing United States yet, which has a five year shelf life. We have a we have a product that is glutathione five and 50 milligrams per ml which is which is actually registered as a medication in China right now. We do have patents in China as well. And so that is that is a five year shelf life that is absolutely stable as a rock right. The via we are making few more products right now for clinical trials, which are not open to the public yet. Because what I want to do is I want to make sure that I will still reserve the right to use a lower cognitive product for masses even if we go for for for drug approval through FDA for the higher concentration one. And so the advice that was given to us was go for the high consumer for the drug trial and leave us the best one for the general public because otherwise you’re going to nothing will be available to the general public ever.
Bill Clearfield 1:34:43
So you can hear me sneezing and coughing and whatnot right last week. I was I wasn’t on here. I was visiting my grandchildren. So of course, now I’m not not not nearly as well as normal. So any use for any use for that. So
1:34:59
So sniffles if it’s if it’s virus, four sprays every four hours for 24 hours. And you’re done.
Bill Clearfield 1:35:06
Okay, good. Okay, and this will be the most important question of the night. When you when you mentioned the fact that you use it to sort of counter counter the effects of alcohol. Do you use the sprays before you go out drinking or after?
1:35:22
So I says you’re supposed to use it after
Bill Clearfield 1:35:25
Burgess wants to know
1:35:28
if you use it before that there’s a good chance it’s gonna take you a while for you to get a buzz. And so so if you want to get the buzz and then use the gluten afterwards. It’s the best thing because you get the best of both worlds. You still get the buzz and you still have you don’t get near the all the cell damage is neurotoxic. And eventually the body will just clip really really fast. And so I use it. I personally use it afterwards. Or actually I use it before it doesn’t really matter because if I get the buzzer it doesn’t bother me that much.
Bill Clearfield 1:36:00
Okay, I thought that would be the probably the most pressing question right?
1:36:06
Would you just can’t glare for cancer survivor? The answer is yes, all day long. I have so many cancer survivor patients they’re using glutathione it’s just I think the word spreading around in the community. All the cancer patients are spreading the word around.
Bill Clearfield 1:36:22
Okay, that’s our job to Dr. Burgess. Do you have anything to add?
1:36:26
This is excellent. I just want to follow through with all of this information. I think we can all work together and help with this great idea. Great project. Fantastic.
Bill Clearfield 1:36:38
Well, thank you very much. Anybody else have anything to ask? Questions? Dr. Patel, it’s always Always a pleasure. Yes.
1:36:48
One question. What about lupus Have you tried it for that?
1:36:53
Yes, yes. Yes. Lupus. So lupus, you got to make sure that you also optimize the hormones too. So androgens you have to optimize the DHEA as well, but the glutathione absolutely helps with the pain apps after the pain right. Unfortunately, they will be on for a long time. I’m talking about years before they can go off to just once they don’t say but the pain should be gone in the first couple of months. fibromyalgia, lupus patients both
Bill Clearfield 1:37:27
Okay, so thanks. Thank you so much.
1:37:31
So my email address if any questions please feel
Bill Clearfield 1:37:34
yes if anybody needs it. Let me know that we were in touch every so often so. I keep trying to strong arm him into taking me on that to help with this hormone. He has a he has a hormone course. too, but you guys want to come to me.
1:37:50
I don’t teach hormone cost by the way. I want to do a one on one. Just if you need help, I don’t teach hormone courses. Rather they go to Dr Clearfield because he has a good program for it. So I just want one only.
Bill Clearfield 1:38:04
Okay the five bucks will be in the mail tomorrow. Thank you. So thank you again Dr. Patel. I can’t thank you enough for for your help and your encouragement your the way you support us. And we’ll we’ll certainly want to, you know, down the road. Have you come back again, anybody who who didn’t get the link? Let me know. We’ll get it to you. I’ll see if I can put it up on the website. Also. If you’re looking for Dr. Hartman’s lecture from last week, I was a little bit tardy. It did go off today so it should be there within the next 24 hours. Next week. We have something a little different. We have Dr. Marlene Siegel, who’s just joined us a couple of weeks ago and she’s our integrative veterinarian and she’s going to enlighten us about what she does. I think I just thought it would be something a little bit different. I think we’re gonna find it quite quite interesting. So if you’re still Yeah, Dr. Siegel, still what? Thank you and again, welcome. I’m really excited to present. Okay, we’re happy to have you. So anybody, anybody who wants to has anything that they’d like to present, let me know. You know, Tuesday nights are for forever in a day. And we have we have the week after Dr. Siegel. We have John Cummings, who runs body site if those of you I’ve used it sites. It’s a program for sort of lifestyle. He’s got a zillion in one. You name the diet, diet plan, and he’s got it programmed in there. You hit a button you type in the patient’s name and they get for 30 or 60 days to get recipes and menus and he’s got every bite you can think of in there. There’s exercise videos, there’s recipes, and he’s going to be on two weeks. And I wrote it down now because it might remember my my calendar, I got all wiped out. After that we have Dr. Watts, he’s going to speak on some sort of some thyroid issue. Brad watts, he does his Friday morning thing. So we have some good some good folks coming up. And again, if anybody wants to volunteer or wants to present please let me know. You know we we only bite patients or their speakers on Thursdays so you’ll be safe here. So so again next week, Dr. Patel again, thank you so much. If there’s anything we can do for you, please let us know. And we’ll see if we can get you some some of our practitioners, you know, using your your products. You got a lot of attaboys great presentations in the chats here. And a lot of thank yous, and again, it’s always a pleasure. I hope to see you soon are you you have any conferences coming up? We are going to be at?
1:41:09
I have a lot of conference coming up this year. So
Bill Clearfield 1:41:14
you go to AMG at the end of April.
1:41:16
No, that’s only what I’m not going to know sure because
Bill Clearfield 1:41:19
that’s that’s where I’ll be. So I’ll bring a raincoat give me a couple of bottles of stuff on sell. I’ll sell it in the back room.
1:41:30
any day, any day. Thank you very much.
Bill Clearfield 1:41:32
Okay, thank you all so much. We will see you next week. Same time, same station. Anybody have any comments, questions? Complaints, let me know if you know anybody would like to present please let me know. And again, John and I are we’re still contemplating how we’re going to get deal credits for our we have a an in house conference. So you know in in person conference, so we’ll get to it. So good night, John, you have anything that we’re covered. Okay. All right. All right. Good night, everybody. We’ll see you again next week. Thank you. Oh, and bring a friend so we double our senses. One friend, everybody, one friend.
1:42:15
You too Dr. Patel.
Bill Clearfield 1:42:17
I’ll try. Okay. All right. Thank you.